Question: Would it be happy embedded in a membrane?Īnswer: This would be “no” since DNA is not a hydrophobic molecule, and only hydrophobic molecules would be happy embedded in the hydrophobic interior of a membrane. Question: Is it happy dissolved in the water-based solution in the nucleus?Īnswer: Yes it is since it’s hydrophilic it loves water-based solution! Because the backbone is polar, it is hydrophilic which means that it likes to be immersed in water. It’s polar because the backbone is constructed from alternating ribose sugar and phosphate molecules which are highly polar. Question: Is it a charged molecule? Polar? Non-polar? Question: Are nucleic acids hydrophilic or hydrophobic? Why?Īnswer: DNA is an acid because the phosphate group donates hydrogen which turns it acidic. eThe sugar-phosphate backbone is negatively charged and hydrophilic, which allows the DNA backbone to form bonds with water. Question: What are the 3 parts of a nucleotide? Question: What is the subunit of a nucleic acid?Īnswer: It’s made up of subunits (nucleotides) and there’s 3 parts to nucleotides. Sugar phosphate bond is the structural component of nucleic acids, that consists of bonding between sugars and phosphate groups. Question: Which of our 4 macromolecules is DNA?Īnswer: Out of the 4 (carbohydrates, lipids, proteins, and nucleic acid) DNA is Nucleic Acid! Sugar-phosphate backbone is composed of alternating sugar and phosphate that defines directionality of the molecules which is negatively charged and hydrophilic. Mutagens damaged the DNA strand which leads to change in normal sequencing including base modification and double-strand breaks which is difficult to repair, as a results it eventually produced point mutations, insertions and deletion of DNA sequence.Question: When it comes to DNA structure, are you always thinking “form and function”?Īnswer: Yes because as long as we know how something is shaped and built, it’ll help us understand how it works and what it does! Sugar-phosphate backbone is composed of alternating sugar and phosphate that defines directionality of the molecules which is negatively charged and hydrophilic to allow the DNA backbone to form bonds with water. The stacking interaction shows side-roll-twist, shift-tilt and rise which is more or less constant. Sugar-phosphate backbone produces energy minima matching by simple replacement of bases such as cytosine, guanine, adenine and thymine which shows mutual base position characteristic of the target sequence and it demonstrates one major degree of freedom consisting of torsion angles chi, delta, zeta and pseudorotation phase angle. Phosphodiester bonds are strong covalent bonds that are formed between 3’ and 5’ carbons of two sugar molecules. The strength and properties of the backbone are due to the formation of phosphodiester bonds. The reason of this coiling structure is in order to protect the bases inside it protecting from being damaged from the environment and each turn of this helix is 34nm long in which 10 bases attached per turn. Sugar phosphate bond is the structural component of nucleic acids, that consists of bonding between sugars and phosphate groups. Sugar-phosphate backbone is linked to phosphodiester bond between carbon 4 and CH2 group that attached to phosphate ion thus make the DNA strand as double helix making it twist into a coil. A structural component of DNA that consists of 5-deoxyribose sugars and phosphate groups involved in carrying the genetic code.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |